Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8
USERS' SCORE
Good
Based on 3 Reviews
8.4
Supplement Facts
Serving Size:  2 Tablets
Serving Per Container:  30
Amount Per Serving
%DV
Magnesium (as magnesium citrate)
400 mg
95%
Sodium
10 mg
<1%

Top Medical Research Studies

9
Magnesium sulfate alleviates postoperative pain
We explored the impact of magnesium sulfate on managing pain following total knee arthroplasty. In a randomized, double-blind trial with 90 patients, half received a blend of analgesics that included magnesium sulfate, while the other half did not.

Following surgery, the results showed that magnesium sulfate helped prolong pain relief and reduced the need for opioids. Patients receiving it experienced less postoperative pain and moved towards recovery more effectively.

Overall, adding magnesium sulfate appears beneficial for postoperative knee pain management.
Read More
9
Magnesium aids postoperative pain relief
We explored the role of magnesium in reducing knee pain following total knee arthroplasty (TKA). In a study involving 119 adults, participants received either an adductor canal block with magnesium and bupivacaine or just bupivacaine.

Those who received magnesium reported significantly lower pain scores and reduced opioid usage in the days after surgery, without experiencing an uptick in nausea or dissatisfaction. This suggests that adding magnesium to local anesthesia could enhance pain management for TKA patients, promoting a smoother recovery.
Read More
9
Magnesium reduces postoperative knee pain
We evaluated the impact of magnesium sulphate on pain levels for 44 patients undergoing staged bilateral total knee arthroplasty.

In this study, the magnesium group received magnesium sulphate while the control group received isotonic saline during their surgeries.

Our findings showed that those who received magnesium experienced significantly lower pain scores compared to the control group, both after their first and second surgeries.

Importantly, magnesium also helped reduce the need for additional pain relief medications in the days following surgery.
Read More

Most Useful Reviews

9
Recommended pain relief
The best company! Top quality! Recommended by a doctor! This is a pain relief supplement, more than just vitamins.
Read More
9
Joint pain improvement
These capsules are huge but effective. I took it due to significant muscle and joint pains, and I noticed improvements immediately; I felt better during workouts with less pain and improved recovery after exercising.
Read More
6
Supports joint health
Solgar is among the highest quality companies in dietary supplements, and their ingredients reflect great quality. At 40, I regularly take magnesium, which is beneficial for my joints due to osteochondrosis. I also take chondroitin and hyaluronic acid and practice yoga for a life free of pain and to ensure good sleep.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8
  • All Researches
9
Magnesium sulfate alleviates postoperative pain
We explored the impact of magnesium sulfate on managing pain following total knee arthroplasty. In a randomized, double-blind trial with 90 patients, half received a blend of analgesics that included magnesium sulfate, while the other half did not.

Following surgery, the results showed that magnesium sulfate helped prolong pain relief and reduced the need for opioids. Patients receiving it experienced less postoperative pain and moved towards recovery more effectively.

Overall, adding magnesium sulfate appears beneficial for postoperative knee pain management.
Read More
9
Magnesium aids postoperative pain relief
We explored the role of magnesium in reducing knee pain following total knee arthroplasty (TKA). In a study involving 119 adults, participants received either an adductor canal block with magnesium and bupivacaine or just bupivacaine.

Those who received magnesium reported significantly lower pain scores and reduced opioid usage in the days after surgery, without experiencing an uptick in nausea or dissatisfaction. This suggests that adding magnesium to local anesthesia could enhance pain management for TKA patients, promoting a smoother recovery.
Read More
9
Magnesium and bupivacaine effective
We evaluated how effective magnesium, especially when combined with bupivacaine, is for managing knee pain after arthroscopy. Our study looked at data from 78 randomized trials involving 4,425 participants.

It turns out that magnesium with bupivacaine is the top performer in easing pain right after surgery and at the 24-hour mark, outperforming other analgesics like morphine.

However, magnesium alone didn’t show significant pain relief. We found that using this combination does not lead to more side effects, making it a safe choice for recovery.
Read More
9
Magnesium reduces postoperative knee pain
We evaluated the impact of magnesium sulphate on pain levels for 44 patients undergoing staged bilateral total knee arthroplasty.

In this study, the magnesium group received magnesium sulphate while the control group received isotonic saline during their surgeries.

Our findings showed that those who received magnesium experienced significantly lower pain scores compared to the control group, both after their first and second surgeries.

Importantly, magnesium also helped reduce the need for additional pain relief medications in the days following surgery.
Read More
9
Magnesium reduces post-surgery pain
We looked into how magnesium can help ease knee pain after total knee arthroplasty. In a study of 80 patients, those who received an injection of magnesium sulfate and ropivacaine experienced significantly less pain and needed less morphine compared to those who got a saline injection. This approach not only reduced morphine use in the first 48 hours but also allowed patients to regain movement quicker. Overall, our findings suggest that magnesium may be a beneficial part of pain management in knee surgery.
Read More

User Reviews

USERS' SCORE
Good
Based on 3 Reviews
8.4
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Recommended pain relief
The best company! Top quality! Recommended by a doctor! This is a pain relief supplement, more than just vitamins.
Read More
9
Joint pain improvement
These capsules are huge but effective. I took it due to significant muscle and joint pains, and I noticed improvements immediately; I felt better during workouts with less pain and improved recovery after exercising.
Read More
6
Supports joint health
Solgar is among the highest quality companies in dietary supplements, and their ingredients reflect great quality. At 40, I regularly take magnesium, which is beneficial for my joints due to osteochondrosis. I also take chondroitin and hyaluronic acid and practice yoga for a life free of pain and to ensure good sleep.
Read More

Frequently Asked Questions

9
Joint pain improvement
These capsules are huge but effective. I took it due to significant muscle and joint pains, and I noticed improvements immediately; I felt better during workouts with less pain and improved recovery after exercising.
6
Supports joint health
Solgar is among the highest quality companies in dietary supplements, and their ingredients reflect great quality. At 40, I regularly take magnesium, which is beneficial for my joints due to osteochondrosis. I also take chondroitin and hyaluronic acid and practice yoga for a life free of pain and to ensure good sleep.
9
Magnesium sulfate alleviates postoperative pain
We explored the impact of magnesium sulfate on managing pain following total knee arthroplasty. In a randomized, double-blind trial with 90 patients, half received a blend of analgesics that included magnesium sulfate, while the other half did not.

Following surgery, the results showed that magnesium sulfate helped prolong pain relief and reduced the need for opioids. Patients receiving it experienced less postoperative pain and moved towards recovery more effectively.

Overall, adding magnesium sulfate appears beneficial for postoperative knee pain management.
7
Magnesium aids knee surgery recovery
We investigated how magnesium sulfate influences recovery after knee surgery. In our study, 148 elderly patients undergoing total knee arthroplasty were divided into two groups: one received magnesium sulfate, while the other received a saline solution.

This double-blind setup allowed us to see if magnesium sulfate could enhance recovery quality after surgery. Our findings indicate that magnesium sulfate does help reduce early postoperative pain and improves overall recovery in these patients.

Overall, magnesium sulfate appears beneficial in managing pain during the recovery process.
7
Magnesium intake impacts knee pain
We explored whether magnesium intake affects knee pain and function in individuals with knee osteoarthritis. In a study involving over 2,500 participants, we followed their magnesium intake for 48 months.

Our findings showed that lower magnesium intake was linked to worse pain and reduced function over time. This trend was particularly noticeable in people who also had low fiber intake. These results suggest that maintaining adequate magnesium levels could be beneficial for managing knee pain.
8
Magnesium enhances post-surgery pain relief
We examined the impact of magnesium sulfate paired with levobupivacaine on pain relief after total knee arthroplasty (TKA). In our study, 60 patients were divided into two groups: one received the magnesium cocktail, while the other only got levobupivacaine. Our findings revealed that the magnesium group experienced prolonged pain relief, reduced reliance on additional pain medication, and effective management of early postoperative pain. Overall, this suggests that magnesium sulfate could be a valuable addition to pain management protocols following knee surgery.
9
Magnesium reduces post-surgery pain
We looked into how magnesium can help ease knee pain after total knee arthroplasty. In a study of 80 patients, those who received an injection of magnesium sulfate and ropivacaine experienced significantly less pain and needed less morphine compared to those who got a saline injection. This approach not only reduced morphine use in the first 48 hours but also allowed patients to regain movement quicker. Overall, our findings suggest that magnesium may be a beneficial part of pain management in knee surgery.

References

  1. Zhu Y, Shen S, Cui L, Wu L, Zhang B. Magnesium sulphate and sodium bicarbonate as additives for periarticular local infiltration analgesia improve pain management after unicompartmental knee arthroplasty: a prospective, double-blind, randomized controlled trial. J Orthop Surg Res. 2024;19:764. doi:10.1186/s13018-024-05233-6
  2. Xu H, Hao C, Wang X, Du J, Zhang T, et al. Effect of Magnesium Sulfate Infusion on Postoperative Quality of Recovery in Patients Undergoing Total Knee Arthroplasty: A Prospective, Double-Blind, Randomized Controlled Trial. Drug Des Devel Ther. 2024;18:919. doi:10.2147/DDDT.S444896
  3. Zhao C, Wang L, Chen L, Wang Q, Kang P. Effects of magnesium sulfate on periarticular infiltration analgesia in total knee arthroplasty: a prospective, double-blind, randomized controlled trial. J Orthop Surg Res. 2023;18:301. doi:10.1186/s13018-023-03790-w
  4. Wang Q, Zhao C, Hu J, Ma T, Yang J, et al. Efficacy of a Modified Cocktail for Periarticular Local Infiltration Analgesia in Total Knee Arthroplasty: A Prospective, Double-Blinded, Randomized Controlled Trial. J Bone Joint Surg Am. 2023;105:354. doi:10.2106/JBJS.22.00614
  5. Choi JW, Lahori A, Merlo JA, Gill O, Ghoddoussi F, et al. Adductor Canal Blocks With Bupivacaine and Magnesium After Same-day Discharge Total Knee Arthroplasty Improve Postoperative Pain Relief and Decrease Opioid Consumption: A Prospective Randomized Controlled Trial. Clin J Pain. 2022;38:388. doi:10.1097/AJP.0000000000001036
  6. He Y, He H, Li X, Lei G, Xie D, et al. Intra-Articular Magnesium Plus Bupivacaine Is the Most Effective and Safe Postoperative Analgesic Option Following Knee Arthroscopy: A Network Meta-analysis. Arthroscopy. 2022;38:2897. doi:10.1016/j.arthro.2022.03.013
  7. Shi L, Zhu H, Ma J, Shi LL, Gao F, et al. Intra-articular magnesium to alleviate postoperative pain after arthroscopic knee surgery: a meta-analysis of randomized controlled trials. J Orthop Surg Res. 2021;16:111. doi:10.1186/s13018-021-02264-1
  8. Zhao Z, Zhang X, Peng H, Li W, Liu H, et al. Magnesium Sulfate Combined with a Levobupivacaine Periarticular Cocktail for Analgesia in the Early Postoperative Period after Total Knee Arthroplasty. J Knee Surg. 2021;34:1463. doi:10.1055/s-0040-1710364
  9. Condello V, Filardo G, Madonna V, Andriolo L, Screpis D, et al. Use of a Biomimetic Scaffold for the Treatment of Osteochondral Lesions in Early Osteoarthritis. Biomed Res Int. 2018;2018:7937089. doi:10.1155/2018/7937089
  10. Shmagel A, Onizuka N, Langsetmo L, Vo T, Foley R, et al. Low magnesium intake is associated with increased knee pain in subjects with radiographic knee osteoarthritis: data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2018;26:651. doi:10.1016/j.joca.2018.02.002
  11. Shin HJ, Kim EY, Na HS, Kim TK, Kim MH, et al. Magnesium sulphate attenuates acute postoperative pain and increased pain intensity after surgical injury in staged bilateral total knee arthroplasty: a randomized, double-blinded, placebo-controlled trial. Br J Anaesth. 2016;117:497. doi:10.1093/bja/aew227
  12. Chen Y, Zhang Y, Zhu YL, Fu PL. Efficacy and safety of an intra-operative intra-articular magnesium/ropivacaine injection for pain control following total knee arthroplasty. J Int Med Res. 2012;40:2032.
  13. Ekmekci P, Bengisun ZK, Akan B, Kazbek BK, Ozkan KS, et al. The effect of magnesium added to levobupivacaine for femoral nerve block on postoperative analgesia in patients undergoing ACL reconstruction. Knee Surg Sports Traumatol Arthrosc. 2013;21:1119. doi:10.1007/s00167-012-2093-4
  14. Koltka K, Koknel-Talu G, Asik M, Ozyalcin S. Comparison of efficacy of intraarticular application of magnesium, levobupivacaine and lornoxicam with placebo in arthroscopic surgery. Knee Surg Sports Traumatol Arthrosc. 2011;19:1884. doi:10.1007/s00167-011-1497-x
  15. Chen Y, Zhang Y, Zhu YL, Fu PL. Efficacy and safety of an intra-operative intra-articular magnesium/ropivacaine injection for pain control following total knee arthroplasty. J Int Med Res. 2009;37:1733.
  16. Farouk S, Aly A. A comparison of intra-articular magnesium and/or morphine with bupivacaine for postoperative analgesia after arthroscopic knee surgery. J Anesth. 2009;23:508. doi:10.1007/s00540-009-0822-8
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